Methotrexate Displacement in Man*

Methotrexate Displacement in Man.

Leftward septal displacement during right ventricular loading in man.

Little direct evidence in man indicates that acute right ventricular loading alters left ventricular configuration. We used the Mueller maneuver (forced inspiration against a closed airway) to increase right ventricular loading and evaluated septal shape and right and left ventricular size in nine normal, semisupine men with phased-array, two-dimensional echocardiography. End-systolic and end-d...

the tragedy of modern man in arthur millers world

what miller wants is a theatre of heightened consciousness. he speaks of two passions in a man, the passion to "feel" and the passion "know". he belives that we can have more of the latter. he says: drama is akin to the other inventions of man in that it ought to help us know more and not merely to spend our feelings. the writing of the crucible shows us that he is trying to give more heightene...

The metabolic fate of tritiated methotrexate. II. Absorption and excretion in man.

acid antagonist both iii the treatment of neoplastic dis eases such as acute lymphocytic leukemia of childhood and t.rophoblastic malignancies and in the investigation of a variety of immune phenomena. Although in years past studies of absorption and excretion of MTX were numerous, more recent pharmacologic interest has con cerned the mechanism of action of MTX, and the develop ment of resistan...

Effects of uncertainty and target displacement on the latency of express saccades in man

Saccadic eye movements generated in response to a gap paradigm in which the fixation light spot was extinguished 200 ms prior to presentation of the target light spot showed appreciably shorter latencies than for the overlap paradigm in which the target light spot was presented 200 ms prior to extinction of the fixation light spot. When there was unpredictability in the direction of target pres...